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A. Looking at the country’s population, there are over 50 million women in the US who are over 50. On average, about 6,000 women are starting to go through menopause each day.


A.Studies show that up to 75% of women have hot flashes with menopause. One study* showed that over half of all women have frequent hot flashes. For some women with frequent hot flashes in this study, hot flashes lasted for 7 years, which caused them to feel more anxiety and stress. Talking with your doctor can help you get the treatment you deserve.


A. We can all draw strength from community support. Here are a few online organizations we’ve found helpful:

EmpowHER® an online health site dedicated to women’s health and wellness that features chat rooms, news and relationship advice.

Red Hot Mamas®Educational information about menopause as well as support for physical, social and mental well-being.

North American Menopause Society (NAMS)One of North America’s leading nonprofit organizations that is dedicated to promoting the health and quality of life of women through an understanding of menopause.

Red Hot Mamas®, EmpowHER® and North American Menopause Society are independently operated organizations and not affiliates of Sebela Pharmaceuticals Inc. Sebela assumes no responsibility for these sites and for their content. Sebela contracts with and/or provides support for these organizations.


A. Both moderate and severe hot flashes make you perspire. The difference is:

  • With Moderate hot flashes — you are able to continue activity.
  • With Severe hot flashes — you have to stop whatever activity you’re doing.


A.A recent study of women with frequent hot flashes found that more than 50% of those women experienced them for over 7 years.*


A. Hot flashes frustrate us in everyday life, but these tips may help:

  • Keep track of when you get hot flashes – a diary could help you see if there’s a pattern with your triggers.
  • Go someplace cool when a hot flash starts.
  • Drink something cold.
  • Dress in natural fabric clothes.
  • Wear layers of clothes that you can take off.


A.Suffering with hot flashes can really disrupt your work, home and social activities. Talking with your doctor is a good way to begin getting the help with hot flashes that you deserve. Ask about all your choices. Then together you’ll choose a treatment that’s right for you.

Support You Could Use

Support You Could Use Support You Could Use

Get the help you deserve, from community resources to financial support, make the connection here.

What to Expect

What to Except What to Except

Understanding menopause can help you feel more in control, so start today.

Co-pay Savings

Co-pay Savings Co-pay Savings

Pay as little as $25 for a 90 day supply of Brisdelle. For eligibility and to register, begin here.

Co-pay Savings

Co-pay Savings Co-pay Savings

Pay as little as $25 for a 90 day supply of Brisdelle. For eligibility and to register, begin here.

What to Expect

What to Except What to Except

Understanding menopause can help you feel more in control, so start today.

Support You Could Use

Support You Could Use Support You Could Use

Get the help you deserve, from community resources to financial support, make the connection here.

*Results of a nationwide study published in 2015 by the Journal of the American Medical Association.


For any questions about Brisdelle

Call: 888-246-1207


For any questions about Brisdelle

Call: 888-246-1207


What is the most important information I should know about BRISDELLE?

Call your healthcare provider right away if you have any of the following symptoms, or go to the nearest emergency room:

Suicidal thoughts or actions:

  • BRISDELLE, and related antidepressant medicines, may increase suicidal thoughts or actions within the first few months of treatment.

  • Depression or other serious mental illnesses are the most important causes of suicidal thoughts or actions.

  • Watch for these changes and call your healthcare provider right away if you notice:

    • New or sudden changes in mood, behavior, actions, thoughts, or feelings, especially if severe.

    • Pay particular attention to such changes when BRISDELLE is started.

Keep all follow-up visits with your healthcare provider and call between visits if you are worried about symptoms.

Call your healthcare provider right away or go to the nearest emergency room if you have any of the following symptoms, especially if they are new, worse, or worry you:

  • Attempts to commit suicide; acting on dangerous impulses; acting aggressive or violent; thoughts about suicide or dying; new or worse depression; new or worse anxiety or panic attacks; feeling agitated, restless, angry, or irritable; trouble sleeping; an increase in activity or talking more than what is normal for you or other unusual changes in behavior or mood.

Serotonin Syndrome. This condition can be life-threatening and may include: Nervousness, hallucinations, coma, or other changes in mental status; coordination problems or small movements of the muscles that you cannot control; racing heartbeat, high or low blood pressure; sweating or fever; nausea, vomiting, or diarrhea; muscle rigidity; dizziness; flushing; tremors; seizures.

Reduced effectiveness of tamoxifen: Tamoxifen (a medicine used to treat breast cancer) may not work as well if it is taken at the same time as BRISDELLE. If you are taking tamoxifen, tell your healthcare provider before starting BRISDELLE.

Abnormal bleeding: BRISDELLE may increase your risk of bleeding or bruising, especially if you take the blood thinner warfarin, or non-steroidal anti-inflammatory drugs (NSAIDs), like ibuprofen, naproxen, or aspirin.

Visual symptoms.

Low salt (sodium) levels in the blood: Elderly people may be at greater risk for this. Symptoms may include: headache; weakness or feeling unsteady; confusion, problems concentrating or thinking or memory problems.

Bone Fractures: Women who take BRISDELLE may have a higher risk of bone fractures.

Manic episodes: Greatly increased energy; severe trouble sleeping; racing thoughts; reckless behavior; unusually grand ideas; excessive happiness or irritability; talking more or faster than usual.

Seizures or convulsions.

Restlessness: Women who take BRISDELLE may feel an inner restlessness, nervousness, or be unable to sit still or stand still especially when they start taking BRISDELLE.

Who should not take BRISDELLE?

Do not take BRISDELLE if you:

  • Take a Monoamine Oxidase Inhibitor (MAOI). Ask your healthcare provider or pharmacist if you are not sure if you take an MAOI, including the antibiotic linezolid.

  • Do not take an MAOI within 14 days of stopping BRISDELLE unless directed to do so by your healthcare provider.

  • Do not start BRISDELLE if you stopped taking an MAOI in the last 14 days unless directed to do so by your healthcare provider.

  • People who take BRISDELLE close in time to an MAOI may have serious or life-threatening side effects. Get medical help right away if you have any of these symptoms:

    • High fever, uncontrolled muscle spasms, stiff muscles, rapid changes in heart rate or blood pressure, confusion, loss of consciousness (pass out).

  • Take thioridazine or pimozide. Do not take thioridazine or pimozide together with BRISDELLE because this can cause serious heart problems or sudden death.

  • Are allergic to paroxetine or any of the ingredients in BRISDELLE.

  • Are pregnant. BRISDELLE is not for pregnant women. Paroxetine can harm your unborn baby.

What should I tell my healthcare provider before starting BRISDELLE?

Before starting BRISDELLE, tell your healthcare provider if you:

  • Have liver or kidney problems; bipolar disorder or mania; low sodium levels in your blood; glaucoma (high pressure in the eye); have or had seizures, convulsions, or bleeding problems; have any other medical conditions; are breastfeeding or plan to breastfeed.

Tell your healthcare provider about all the medicines that you take, including prescription and non-prescription medicines such as migraine headache medication (triptans), other antidepressants and antipsychotics, vitamins, and herbal supplements.

If you take BRISDELLE, you should not take any other medicines that contain paroxetine, including Paxil®, Paxil CR®, and Pexeva®.

What should I avoid while taking BRISDELLE?

You should not drive, operate heavy machinery, or do other dangerous activities until you know how BRISDELLE affects you.

What are the most common side effects of BRISDELLE?

The most common possible side effects of BRISDELLE include: headache; tiredness; nausea and vomiting.

Tell your healthcare provider if you have any side effect that bothers you or does not go away. These are not all the possible side effects of BRISDELLE.


BRISDELLE® (paroxetine) capsules is a prescription medicine used to reduce moderate to severe hot flashes associated with menopause.

BRISDELLE is not approved to treat depression or any other psychiatric conditions.

Please read the Medication Guide within the full Prescribing Information before taking BRISDELLE. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call

Brisdelle® and Pexeva® are registered trademarks of Sebela International Ltd. All other registered trademarks are the property of their respective owners.

REREFENCES: 1. Brisdelle [Prescribing Information]. Roswell, GA: Sebela Pharmaceuticals Inc.; 2017. 2. Grady D, Sawaya GF. Discontinuation of postmenopausal hormone therapy. Am J Med. 2005;118(suppl 12B):163S-165S. 3. Avis NE, Crawford DL, Greendale G, et al. Duration of menopausal vasomotor symptoms over the menopause transition. JAMA Intern Med. 2015;175(4):531-539. 4. Freeman EW, Sammel MD, Sanders RJ. Risk of long-term hot flashes after natural menopause: evidence from the Penn Ovarian Aging Study cohort. Menopause. 2014;21(9):924-932.